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We are aware of several study limitations
The gastrointestinal effects of these medications may interact with alcohol consumption
Dual GLP-1/GIP agonists add a second incretin receptor, GIP
The most common side effects of GLP-1 receptor agonists include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort , particularly during the initial weeks of treatment or following dose escalation
For Wegovy, current prescribing information states that escalation is designed to reduce gastrointestinal adverse reactions and allows clinicians to consider delaying escalation when a dose is not tolerated
Most are mild and temporary
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