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But even as he calls for more robust data on long-term outcomes and safety in older adults, Batsis says that his skepticism regarding the benefits of these drugs has decreased over the past few years

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Recent studies indicate that the absence of MT1 receptors in mice leads to increased nocturnal IOP and a decrease in RGCs, highlighting a possible connection between impaired melatonin signaling and the development of glaucoma (68)

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