797 Even neonatal rat ventricular muscle cells with low sensitivity to GPX4 inhibition underwent ferroptosis in the presence of cysteine deprivation, suggesting that inhibition of GPX4 promotes ferroptosis of cardiomyocytes under metabolic stress, such as cysteine deprivation
More studies are needed to explore this mechanism further, not least given the advent of medications targeting antioxidant systems which may be an important future therapeutic option in patients with MDD (Simon et al
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Bioinformatics analysis of ferroptosis in spinal cord injury
Ante un compuesto sin aprobacin regulatoria y con datos humanos limitados, la actitud responsable es minimizar la exposicin al riesgo