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Existing tree-based IRT models have been developed for binary and polytomous items within the Rasch models framework, which assume equal discrimination (i.e., the degree to which an item distinguishes between individuals with different levels of the latent construct) across items
The possibility that the protection of HSC-depleted mice from APAP challenge may be partly related to the inadequacy of such modulated relationship between HSCs and KCs [53]
The Role of Antioxidants in Supporting Detoxification Processes Antioxidants can help support the body's detoxification processes by neutralizing free radicals and reducing oxidative stress, which can damage cells and impair detoxification mechanisms
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However, this outcome highlights a significant translational paradox