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Thomas Idorn: Conceptualization

Patients with A1C 8% at screening had their background basal insulin dose reduced by 20% at the start of the trial to limit potential risk of hypoglycemia

Sitagliptin phosphate monohydrate is described chemically as 7 - [(3R) - 3 - amino - 1 - oxo - 4 - (2,4,5 - trifluorophenyl)butyl] - 5,6,7,8 - tetrahydro - 3 - (trifluoromethyl) - 1,2,4 - triazolo[4,3 - a]pyrazine phosphate (1:1) monohydrate with an empirical formula of C 16 H 15 F 6 N 5 O-H 3 PO 4 -H 2 O and a molecular weight of 523.32

PubMed laboratory research record [PMID: 41680520] PubMed record related to this compound for laboratory literature review

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The approval also demonstrates that a blockbuster class of diabetes and weight loss drugs called GLP-1s have significant health benefits beyond regulating blood sugar and suppressing appetite