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Rapid improvement in glucose control has been associated with a temporary worsening of diabetic retinopathy

Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2.4 mg for weight management: A randomised, controlled, phase 1b trial

The difference is straightforward

BPC-157 is a synthetic peptide derived from a protective protein naturally found in human gastric juice

There is no robust body of randomized controlled trial data demonstrating that lipotropic injections cause clinically significant fat loss beyond what the accompanying calorie restriction, activity changes, and clinical monitoring would have produced anyway

FDA statement FDA