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10.1016/j.neuint.2005.10.002 Neurochem
Simple nutrition and hydration measures substantially reduce side-effect burden: roughly 70% of patients report early nausea when starting semaglutide, and about 50% report fewer side effects after diet and fluid adjustments
Other contributing factors include: Small intestinal bacterial overgrowth (SIBO) Gastrointestinal infections or parasites Certain medicines that slow digestion (e.g., opioids, anticholinergics, tricyclic antidepressants, GLP-1 receptor agonists) Food intolerances or malabsorption disorders Swallowing excess air (aerophagia) Consumption of carbonated beverages Understanding the underlying cause is essential for effective management
Lanciotti M et al
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