The most significant results came from the in vivo animal studies
By month two, something shifted
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For most patients, GLP-1-related bloating improves after dose stabilization, typically within 4 weeks to several months
10.1002/gps.4486 Summary Keywords N-acetyl cysteine, antioxidant, multiple sclerosis, cerebral glucose metabolism, positron emission tomography, cognition Citation Monti DA, Zabrecky G, Leist TP, Wintering N, Bazzan AJ, Zhan T and Newberg AB (2020) N-acetyl Cysteine Administration Is Associated With Increased Cerebral Glucose Metabolism in Patients With Multiple Sclerosis: An Exploratory Study
While these observational data are encouraging, randomized clinical trials are needed before this approach can be incorporated into routine PAD management