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In Canada, the non-formulary claims for GLP-1 RAs increased by more than fourfold from 14,088 claimants in 2016 to 60,120 claimants in 2021 [6]

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2016 measured 55.8% wrinkle volume reduction and 32.8% depth reduction over 12 weeks, with a 31.6% greater reduction than Matrixyl 3000 in head-to-head testing

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