Efocipegtrutide shows potential benefits in obesity, MASLD/fibrosis, dyslipidemia, and even neuroinflammation in preclinical models
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Although the patients body weight temporarily decreased from 92.4 kg to 90.8 kg during the first 3 months of treatment, it returned to 92.0 kg over the following 6 months ( Supplementary Figure 1 )
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Reduced GSH levels due to impaired GCL activity is unlikely to be replenished by other GSH precursors such as NAC or other cysteine prodrugs
2017 Oct