Experts do not recommend B12 shots for weight loss
They want reliable documentation, verified quality, and a source they can review with confidence before placing an order
External resources for tirzepatide and B12 research Clinical trial data for tirzepatide weight loss efficacy comes primarily from the SURMOUNT trial series published in The New England Journal of Medicine
That alone is a major practical advantage
In addition to impacting the speed of absorption of oral supplements, the digestive process also affects the extent of absorption, with 40%-50% of low-dose B12 vitamins being absorbable
Sanz-Cuesta T, Escortell-Mayor E, Cura-Gonzalez I et al (2020) Oral versus intramuscular administration of vitamin B12 for vitamin B12 deficiency in primary care: a pragmatic, randomized, non-inferiority clinical trial (OB12)