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These bloated cells become resistant to insulin, which helps break down glucose, and trigger inflammation that can cause tissue damage

UP Xchange is also where the conversation around consultations really deepens: how to talk to patients about skin changes, set expectations early, and guide them through a long-term plan with confidence

Another cause may be inflammation of the uvea (middle layer of the eye) or bleeding in the vitreous due to diabetes, hypertension, or injury

In addition, the high cost of GLP-1 therapies remains a barrier, especially in markets with limited insurance coverage or constrained healthcare budgets The annual cost of treatment with drugs such as Wegovy or Zepbound can exceed several thousand dollars, which may limit accessibility for patients without comprehensive health coverage

17.2 Supportive Treatment and Medical Intervention Management is primarily supportive

Wear protective clothing and seek shade when outdoors