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LPS induces potent immune activation in several cell types, including T cells, NK cells 57 , dendritic cells 58 and macrophages 59
& Sznitman, J
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GSTs conjugate 4HNE to GSH, and the corresponding glutathionyl-4-HNE (GS-HNE) is actively transported out of cells via RLIP76, a multifunctional membrane transporter for GSH-conjugated compounds, and/or MRPs (multidrug-resistance proteins
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