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These include: Metformin (used for diabetes or PCOS) Proton Pump Inhibitors (used for acid reflux or GERD) H2 Blockers Birth control pills Certain antibiotics If youre taking these medications long-term, particularly in combination, regular B12 injections might be beneficial

But if you get them from a trusted source (more on that below), it couldnt be safer or easier

The frequency depends on your individual needs and the severity of any deficiency

Because B12 vitamin is bound to amino acids (found in protein foods) and is only released when certain enzymes and stomach acids are present, its possible to consume enough but still remain somewhat deficient

Methyl group (position 1): also important for effective inhibition

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