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Enzymatic conjugation of chlorambucil with glutathione by research-subject glutathione S-transferases and inhibition by ethacrynic acid

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Pyroptosis A form of programmed cell death triggered by infection or cellular stress that is, unlike apoptosis, characterized by inflammation as it involves the activation of inflammasomes and caspase-1, leading to cell swelling, membrane rupture and the release of pro-inflammatory cytokines such as interleukin-1 (IL-1) and IL-18

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This ensures the needle reaches the muscle tissue effectively