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Remove any safety device from the needle
An earlier 12-week trial in 300 obese adults produced a genuine positive signal the 1 mg daily dosing arm showed a statistically significant 2.8 kg mean weight loss versus 0.8 kg in the placebo group and that result is what justified moving into the larger Phase IIb trial
Second, the doses are small because the target is a high-affinity intracellular enzyme, not a receptor that needs saturating with milligrams of drug
Knowing the right doses and how to give them is important
Does Everyone Actually Need a B12 Injection
While generally well-tolerated, some individuals may experience side effects such as: Irritation or redness at the injection site Temporary fatigue or nausea Immediate medical consultation is recommended if you experience severe side effects or allergic reactions
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