10.1038/cddis.2014.358 309 YordyB.IijimaN.HuttnerA.LeibD.IwasakiA
doi: 10.2174/1570159X18666200207120949 10 OeckinghausAHaydenMSGhoshS
Chlorogenic acid inhibited APAP-induced activation of caspase-3 and caspase-7, JNK, ERK1/2, and upstream molecular signaling of p38 MAPKs in animals, including apoptosis signal-regulated kinase 1 (ASK1), c-Raf, and Mitogen-activated protein kinases MEK1/2, MKK3/6 and MKK4 (Wei et al., 2018)
KPV for inflammation, GHK-Cu for barrier repair, and antimicrobial peptide support for microbial balance represent the comprehensive approach
doi: 10.1016/s0009-8981(03)00200-6
Two trials in acutely hospitalized patients have shown that short-term (around 7 days) vitamin C supplementation increased concentrations of ascorbic acid in plasma and leukocytes and led to 34-35% improvements in mood state, as measured by POMS (142, 143)