Immunopharmacol Immunotoxicol 2003;25(2):25971.ArticlePubMed [38] Ben-Arie E, Lottering B, Inprasit C, Yip HT, Ho WC, Ton G, et al
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Peripherally administered liraglutide has direct access to a limited number of brain regions, primarily circumventricular organs and a few sites in the hypothalamus (8), and CNS GLP-1Rs are important for its body weightlowering (BW-lowering) effect (9)
One of the primary manifestations is muscle weakness and functional decline