Vomiting, diarrhea, constipation, and reflux symptoms are also reported
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In a different network meta-analysis that included over 40,000 patients with atrial fibrillation and valvular heart disease, apixaban had a lower risk of major bleeding events compared with the other DOACs and warfarin
Sulforaphane can support osteoblast differentiation ( via epigenetic mechanisms) and expression of the osteoclast activator receptor activator of nuclear factor-B ligand (RANKL) in osteocytes (Thaler et al., 2016)
Its review would address safety, effectiveness, and quality
The 5mg, 10mg, and 15mg maintenance doses correspond exactly to the trial arms