However, it is difficult to separate these two aspects in the current study design
Adverse reactions following intramuscular (IM) injection have included anxiety, mild transient diarrhea, ataxia, nervousness, pruritus, transitory exanthema, and a feeling of swelling of the entire body
Glucagon-like peptide-1 (GLP-1) receptor agonists are a family of antihyperglycemic drugs that have demonstrated potent HbA1c reduction, low risk of hypoglycemia, with associated weight reduction, and proven cardiovascular and renal benefits.24 In this review we describe this type of drugs, their cardiovascular and renal benefits, as well as their clinical potential in patients with DKD, especially with the new oral semaglutide formulation, now available on the market
RZ: Investigation, Methodology, Writing review & editing
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Clinical evidence consistently demonstrates that patients regain approximately one-third of lost weight within the first year of stopping GLP-1 therapy, with longer-term studies suggesting even more substantial rebound [50]