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Differential observations suggest that the role of caveolin 1 in hepatic lipid accumulation may differ depending on how the steatosis is induced, e.g., via high fat diet or fasting
First, it acts as a vehicle of copper, an element essential for multiple enzymes responsible for connective tissue formation, antioxidant activity, and cellular respiration
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These data indicate that genes associated with metabolic ROS generation tend to be upregulated in MZB compared to FoB, suggesting that differences in the control of ROS signaling might contribute to the classical distinctions between these two mature B cell subsets
ALC treatment increases DA and 5-HT release and receptor activity while decreasing the 5-hydroxyindoleacetic acid (5-HIAA)/5-HT ratio, the latter representing lower 5-HT turnover (Sarzi-Puttini et al