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Eerste GLP-1 medicijn goedgekeurd voor MASH in Europa Europa keurt eerste GLP-1 medicijn goed voor MASH-behandeling

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The American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) recommend an A1C level of 6.5% or less for diabetics without concurrent serious illness and low hypoglycemia risk, and a level of about 6.5% - 7% for those with concurrent illnesses or increased hypoglycemia risk (Garber 2020)

Figure 1 PLC- is not only distributed on the cytoplasmic membrane, but also in the nucleus and cytoplasm