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If the MinuteClinic Primary Care offices were to completely fill their patient panels, the commission projected annual spending would increase by $91.5 million

Acknowledgements Cristian-Daniel Llach received the support of a fellowship from la Caixa Foundation (ID 100010434 - fellowship code LCF/BQ/EU22/11930062)

After this loading phase, frequency tapers to weekly injections for four to six weeks, then transitions to monthly maintenance doses

Finally, restrain-free production run was carried out for each simulation, with a time step of 2 fs in the NPT ensemble at 310 K and 1 bar using the Nose-Hoover thermostat and the semi-isotropic Parrinello-Rahman barostat 68 , respectively