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This therapeutic effect cannot be achieved merely by depleting GSH to assist PDT

Intravenous (IV) glutathione injections have been surrounded with some controversy among medical practitioners, mainly because of concerns of safety unrelated to those of oral or topical products of glutathione

It appears more selective and possibly safer than older senolytic approaches

Clin Neuropharmacol 36:103106 Remington R, Lortie JJ, Hoffmann H, Page R, Morrell C, Shea TB (2015) A nutritional formulation for cognitive performance in mild cognitive impairment: a placebo-controlled trial with an open-label extension

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Exclusion criteria in studies typically include Wilson's disease, copper allergy, and pregnancy due to insufficient data in those populations