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Antioxidants are adjunctive to medical therapy Oral antioxidants include vitamin B, C, polypodium, glutathione & melatonin Topical antioxidants include vitamin B, C, E, & ferulic acid Oral antioxidants are easier to use for most patients Topical antioxidants can be considered in some patients Skin irritation is the most common side effect of topical antioxidants, esp

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Migraine patients often have gastro-intestinal complaints such as diarrhea, nausea or vomiting, which can occur as a symptom of the migraine or as an adverse side effect of treatment [264]