Apparently the underlying thought is that it is necessary to keep the value between the (upper and lower) reference values
A recent systematic review and meta-analysis of 21 randomized, placebo-controlled trials examining the effect of B-vitamin supplementation found the supplementation decreased homocysteine concentrations and improved measures global cognitive function but had no effect on individual measures of executive function, information processing speed, or episodic memory (89)
Serious but rare risks include pancreatitis, kidney injury, gallbladder disease, and based on animal studies a potential risk of thyroid C-cell tumors
Once the original container is opened, the water is exposed to potential contamination from the surrounding environment
Over-supplementation without need can cause interactions with other nutrients or mild digestive issues
Using the same spot repeatedly leads to tissue changes that affect how well the medication works and how comfortable the injections feel