The result is targeted mobilization of the most dangerous fat compartment
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This is particularly beneficial for individuals with type 2 diabetes, as it can lead to better blood sugar management alongside weight loss
Avoid going overboard with your tanning injections
However, despite these advantages, the clinical use of native GLP-1 is significantly limited by its short plasma half-life (12 min), owing to rapid enzymatic degradation by DPP-4 and renal clearance
In practice, though, many IBS-C patients on semaglutide need to be proactive with constipation-countering measures (more on strategies in the next section)