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Although the vast majority of studies have revealed interactions between cocaine responses and GLP-1R, some studies have reported correlations between the responses to cocaine and the plasma levels of GLP-1

As weve discussed, semaglutide and similar drugs can modulate gut motility in ways that sometimes align favourably with IBS (e.g

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That changed with the SURMOUNT-5 trial, published in the New England Journal of Medicine in May 2025the first head-to-head comparison

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