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The latter route has a large advantage of adding circulation time to the drug, allowing long-lasting effects of the drugs, potentially reducing the administration frequency and possibly also lowering gastrointestinal complications, as currently only subcutaneous and very few oral routes have been explored

Common week one experiences include mild appetite reduction that comes and goes, slight changes in how food tastes or appeals, occasional mild nausea, particularly after larger meals, and a subtle sense of fullness that arrives earlier during meals than usual

Mashayekhi, M., Nian, H., Mayfield, D., Devin, J

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