Interestingly, the size of the molecule affects its behavior: Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair
AOD-9604 liberates fat from adipocytes, but liberated fat sitting in plasma does nothing except potentially raise LDL-C if it's not oxidised
J Am Coll Cardiol 2024;84:696-708.ArticlePubMed 83
One trial involving 24 Asian women used a cream with niacinamide 5%, tranexamic acid 2%, oxyresveratrol 2%, glutathione disulfide 2%, and linoleic acid 1% applied twice daily
Pinti MV, Fink GK, Hathaway QA, Durr AJ, Kunovac A, Hollander JM
Anti-GLUT1 (Abcam ab195359) diluted 1:200 was used and expression was measured on FoB gated on total splenocytes as described above