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In test-tube studies, alpha-lipoic acid has reduced markers of inflammation, including NF-kB, ICAM-1, VCAM-1, MMP-2, MMP-9, and IL-6 ( May lower heart disease risk factors Heart disease is responsible for one in four deaths in America ( Research from a combination of lab, animal, and human studies has shown that the antioxidant properties of alpha-lipoic acid may lower several heart disease risk factors

Best overall: Thorne Vitamin B12 | Skip to review Best multivitamin with B12: Mindbodygreen Ultimate Multivitamin+ | Skip to review Best vegan: HUM Nutrition B12 Turbo | Skip to review Best liquid B12: Pure Encapsulations B12 Liquid | Skip to review Best gummy: OLLY Daily Energy Gummies | Skip to review Best whole-foods supplement: Garden of Life Vitamin Code Raw B12 Capsules | Skip to review Most affordable: Nature Made B12 Softgels | Skip to review Best allergen-free: Pure Encapsulations Methylcobalamin Capsules | Skip to review Best B complex vitamin: Nordic Naturals Vitamin B Complex | Skip to review Vitamin B12 is an essential dietary nutrient necessary for energy production and proper functioning of your nervous system, among other important roles
Data analysis involved normalization to appropriate controls and determining the enrichment of the target protein
Effects, risks, and legal status vary
Ohtsu, E., Ichiyama, A., Nishizuka, Y