In the OCTN2 occluded conformation, R471 is involved in a hydrogen bonding interaction with S467, coordinating both the hydroxyl and the backbone carbonyl at the point where the lower segment of TM11 kinks toward TM2 in the occluded conformation
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The peptide dosage calculation guide walks through these volume tradeoffs in more detail, and the syringe dosage conversion chart gives you a visual reference for reading your syringe correctly