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Compound 36 also exhibited good efficacy in oral glucose tolerance tests, demonstrating great DPP-4 inhibitory activity (IC 50 = 0.017 M) and moderate selectivity against DPP-4 in both ICR and KKAy mice

The actual clinical evidence for resM specifically is still developing, with a randomized, placebo-controlled trial currently in progress at ClinicalTrials.gov

Cardiac Electrophysiology The effect of subcutaneously administered semaglutide on cardiac repolarization was tested in a thorough QTc trial

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