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Firstly, using the CPRD allowed for the ability to adjust for important potential confounders, including cardiovascular risk factors, microvascular and macrovascular complications, body mass index, and laboratory measures, which are often unavailable in other datasets

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You might want to maintain your new weight for a while before pregnancy

In most cases, small and repeatable habits are easier to maintain long-term

All animals were maintained under identical housing, handling, and dietary conditions, except for experimental treatments

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