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That might mean focusing more on lifestyle changes, switching medications, or considering bariatric surgery. For some patients, surgical options such as sleeve gastrectomy may be appropriate, particularly if they want a more durable intervention

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34 These studies suggest that the impact of lifestyle interventions on breast cancer recurrence may be mediated by effective weight loss and adherence, and importantly, even modest weight change can be associated with meaningful clinical benefit

Resmetirom also has drug interactions and requires lab monitoring, while GLP-1 therapies generally do not