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Under oral administration, the prominently ranked adverse events (AE) include obstructive pancreatitis, thyroid cyst, neck mass, pancreatitis, gallstones, diabetic retinopathy, and gastric emptying disorders

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however it increases when used in conjunction with insulin or insulin secretagogues (Garber 2011)

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Lyophilised Dihexa remains stable for 1224 months at 20C, but once reconstituted, it must be refrigerated at 28C and used within 28 days to prevent hydrolysis and bacterial contamination