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Retatrutide at doses of 4 mg or higher significantly reduced fasting insulin (by 37% to 71%), HOMA2-IR (a measure of insulin resistance, reduced by 36% to 69%), and increased adiponectin (by 30% to 99%)

Ideally, GLP-1s/GIPs not only lead to weight loss and improved metabolic health, they also enable patients to cement healthy habits gained in the process

DeSapri recommends limiting alcohol intake and aiming for eating habits more in line with the Mediterranean diet prioritizing plant-based foods and increasing fiber and protein intake while decreasing sugar intake

Dinner options designed for reduced appetite: Baked cod with roasted asparagus and a small sweet potato (28g protein) Turkey meatballs over zucchini noodles with marinara sauce (30g protein) Chicken breast with steamed broccoli and quinoa (35g protein) Tofu stir-fry with bell peppers, snap peas, and cashews over cauliflower rice (22g protein) Lean beef burger, no bun, over a bed of mixed greens with tomato and avocado (28g protein) Keep dinner lighter than lunch when possible

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Enhancing Gasdermin-induced tumor pyroptosis through preventing ESCRT-dependent cell membrane repair augments antitumor immune response