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Although gut microbiota dysbiosis in PD is extensively analyzed, its causal mechanisms and the possibilities for intervention still require further research [107, 108] (Fig

Also, when compared to their healthy peers, vitiligo patients have a high serological concentration (Shi et al., 2016) and different miRNA profile expression in PBMC (Shi et al., 2013) that can characterize this population

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According to the included studies, lycopene may show high promise in the management of digestive precancerous lesions, such as relieving mouth opening and burning sensation of oral submucous fibrosis (OSF), presenting potentially equivalent efficacy on managing oral lichen planus (OLP) as steroids and alleviating gastrointestinal precancers symptoms, meanwhile lowering colon cancer risk

Wright ME, Lawson KA, Weinstein SJ, et al