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Cells were washed with cold PBS and total proteins were extracted with RIPA buffer containing Halt inhibitors (Thermofisher, MA)

In the human body, the PLG polymers slowly degrade through the non-catalyzed hydrolysis of the ester linkages into lactic acid and glycolic acid, which are finally eliminated as carbon dioxide and water

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Shortly after completing the PTZ challenge, epilepsy behavior was detected for 30 min and recorded on the computer via a connected camera