In Cohort 1, 25 WT and 25 RAMP1/3 KO male mice aged 1220 weeks old were injected intraperitoneally after a 12-hour fast with vehicle, sCT at doses of 3 or 150 nmol/kg, or Cagrilintide at a dose of3 nmol/kg
Discomfort is minimal and resolves within seconds
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Saxon DR, Iwamoto SJ, Mettenbrink CJ, McCormick E, Arterburn D, Daley MF, et al
The same principle applies to growth hormone-releasing peptides like hexarelin and ipamorelin