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Memorial Sloan Kettering Cancer Center
When we are stepping up to injectables, there is not just an onus on authenticating the chemical compound but infection control, stability of the substance, expiry certification and safe injectable techniques need to be added to the quality assurance processes. RACGP President Dr Nicole Higgins has also raised safety concerns and referenced a recent warning from the US Food and Drug Administration about the fact that salt-based semaglutide has not yet been found to be safe or effective by a regulator
The STEP trials demonstrated that participants who continued semaglutide for 68 weeks maintained significant weight loss, while those who switched to placebo regained approximately two-thirds of lost weight within one year
Understanding what to expect and how to respond keeps protocols on track rather than abandoned prematurely
Its conclusion is that the extra pathway warrants individualized risk assessment rather than a blanket ranking
Some compounded versions have been found to contain semaglutide salts, which have not been proven safe or effective
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