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Coskun T, Urva S, Roell WC, Qu H, Loghin C, Moyers JS, OFarrell LS, Briere DA, Sloop KW, Thomas MK, Pirro V, Wainscott DB, Willard FS, Abernathy M, Morford L, Du Y, Benson C, Gimeno RE, Haupt A, Milicevic Z (2022) LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: from discovery to clinical proof of concept

Research continues into its effects on hepatic fat, lipid profiles, and insulin sensitivity

Results: Several studies have discussed the CV beneficial effects of GLP-1 RAs in terms of reducing blood pressure, lipid levels, body weight, risk for arrhythmias, reducing the risk of major adverse CV events, and hospital admission for heart failure

This combination of eating less and burning more is what produces the significant weight loss numbers seen in early research

If you are interested in learning how another medication compares over time, read about tirzepatide weight loss results and timeline

Prioritise Protein to Preserve Muscle Many people underestimate how much protein they actually need, especially when trying to lose weight