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Zapata-Muoz J, Villarejo-Zori B, Largo-Barrientos P, Boya P
The STEP UP Phase 3b clinical trial, published in The Lancet Diabetes and Endocrinology in 2025, enrolled over 1,400 adults with obesity and without diabetes
The signal weakens
Split up reconstituted peptide into small amounts to avoid freeze-thaw cycles
Staying well-hydrated is important, particularly if experiencing gastrointestinal symptoms
Human data: Human exposure is limited and largely unpublished
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