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Semaglutide doesnt prevent pregnancy, and improved metabolic health may actually enhance fertility

The impact of insulin secretion on the ovarian response to exogenous gonadotropins in polycystic ovary syndrome

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The compounding of estrogen decline and GH decline in the same window produces particularly pronounced fatigue, body composition changes, and sleep disruption

Diabetologia 55 , 29702984 (2012)

In contrast, those on higher doses for obesity treatment might experience more pronounced gastrointestinal side effects, including heartburn and acid regurgitation