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However, several challenges remain in translating current SIRT1-targeted strategies from experimental studies to clinical application
mTORC2 also phosphorylates SGK-1 at Ser422, leading to inhibitory phosphorylation of FoxO3 and other activators of autophagy, such as VDAC1 and ULK1 [296]
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Endocrinology 157(11):44464460
Small-molecule fluorescent probes for binding-and activity-based sensing of redox-active biological metals
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