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Several studies suggest that antidepressants like the selective serotonin reuptake inhibitor (SSRI) fluoxetine increase BDNF levels and are dependent on normal TrkB signaling to elicit their behavioral effects [262, 263]

PD is associated with severe loss of dopamine (DA) neurons in the substantia nigra (SN) and their striatal terminals, leading to dopamine depletion and consequential motor impairments

Research shows that sleep deprivation significantly reduces glutathione levels in the brain and liver

Some protocols may use post-workout timing to maximize nutrient partitioning to muscle tissue

These are explained more in detail below

By activating specific receptors and signaling pathways throughout the body, it can help individuals build more lean muscle mass while improving overall metabolic function