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Professor Linong Ji, the principal investigator of the study, Peking University People's Hospital, stated, "Accumulated evidence showed that Chinese people generally have higher percentages of body fat and higher rates of cardiovascular risk factors and all-cause mortality than western population at given BMI levels, therefore overweight and obesity in adults in China are defined with lower BMI cutoffs (overweight cutoff BMI 24 kg/m 2 , obesity cutoff BMI 28 kg/m 2 )

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Patients with a history of diabetic retinopathy should be monitored for progression, and patients should be monitored for depression or suicidal thoughts

However, side effects also follow dose dependent patterns

These effects are typically dose-dependent and tend to be most pronounced during the initial weeks of treatment or following dose escalation

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