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Clinical trials commonly use doses of 750 mg of spermidine-rich plant extract, corresponding to approximately 12 mg of pure spermidine per day (Reference Schwarz, Horn and Benson19)

Furthermore, given the fact that danger signals often change multiple times in lipid metabolism, developing more potent activators/inhibitors that target multiple FAO signaling pathways, including the CPT system or combined with other anti-inflammatory/antitumor therapeutics, may facilitate translation of this promising strategy into clinical application

Invest Urol 19 : 6263 de la Peyronie F (1743) Sur quelque obstacles qui s'opposent a l'ejaculation naturelle de la semence

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