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However, in the posterior cortex, CAT activity was reduced in the VPA+LipRSV group compared to the VPA group, indicating that LipRSV treatment may have negatively modulated the enzymes expression or activity, either by attenuating oxidative stress and thus reducing enzymatic defense needs, or through a possible pro-oxidant effect dependent on the region and experimental conditions

Hill JA, Polgar K, Anderson DJ

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However, there is a difference between the glutathione your body makes and the concentrated doses found in supplements

2000 Sep 18;192(6):907-12