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Nevertheless, previous genetic study employing Mendelian randomization [32] found no evidence supporting a causal role of depression liability in influencing AC levels

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Will Bulsiewicz: And you know what's interesting About this all, Bob, you're an endocrinologist, so that means that you specialize in hormones, is that it starts to paint a picture that obesity may be a hormonally mediated disease

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Consistent with this, Bbs5 / mice displayed a decrease in total eWAT CD4 + T cells compared with WT controls (Figure 3I)